WHO alarm for Enterovirus E11 in France: seven newborns died in recent months
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Alert from the World Health Organization on a type of enterovirus, theEchovirus-11 (E-11)associated with increasing cases of neonatal sepsis with hepatic impairment and multiple organ failure.
Serious cases in hospitals
The WHO warning starts from a report that arrived from France on 5 May: from July 2022 to April 2023, the country beyond the Alps recorded 9 cases in 4 hospitals in 3 regions; as of May 5, 7 newborns have died, the other 2 still hospitalized.
“The current increase in the incidence and severity” of the infection “in newborns, associated with a recombinant lineage of E-11 that had not previously been detected in France, is considered unusual – explains the Geneva agency – due of the extremely rapid deterioration and associated mortality rate among affected children”.
Pediatric viruses, after the pandemic they return (and out of season)
by Tina Simoniello
The risks to public health
“Based on the limited information available,” WHO assesses the “public health risk to the general population as low, despite the worrying nature of the increase” reported.
Enterovirus, Echovirus E-11 and disease
Enteroviruses are a group of viruses that can cause various infectious diseases and are responsible for annual epidemics. The disease is usually mild, but has been found to affect infants differently and sometimes more severely than older children and adults.
How it is transmitted
There are multiple routes of transmission, particularly in the neonatal period, including the intrapartum period for exposure to maternal blood, secretions and/or feces, or postnatal for close contact with infected healthcare workers.
How the disease manifests itself
Infections can cause severe inflammatory disease in newborns, including severe acute hepatitis with coagulopathy.
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